- Anspach
 - Offers manufacture and world wide distribution of surgical instrumentation for the orthopaedic and neurosurgical markets.  CH Medical Ltd
- Manufactures and markets specialist orthopaedic trauma implants and a range of anaesthesia consumable products.- Corin Group
- Manufacturers of partial and total knee, shoulder, and hip replacement joints for use in orthopaedic surgery.
- Depuy
- Designs, manufactures, and distributes orthopaedic devices and supplies.
- Feldinger Technological Ind. Ltd.
- Manufacturers of orthopaedic supports and rehabilitation aids.
- HealthTronics
- Provider of urological and orthopaedic services and products as well as speciality vehicles for medical, broadcast, and security uses.
- Immedica
- Manufacturer of bone cement mixing and delivery systems, trauma implants and instrumentation, and other orthopaedic instruments.
- Innomed, Inc.
- Manufactures and markets orthopaedic surgery instruments.
- Kyphon
- Develops medical balloon devices to assist in the management of fractures involving crushed or collapsed bone.
- MicroAire Surgical Instruments
- Produces orthopaedic surgical power instruments, burs, blades, pulse lavage irrigation and toe implants.
- Smith & Nephew@
- SouthTech Orthopedics
- Distributor of orthopaedic and spine surgery products.
- Synvasive Technology
- Develops, manufactures, and distributes orthopaedic instruments, including knee implant cutting guides and surgical sawblades.
- Tartan Orthopedics
- Wholesaler manufacturer of sport and back supports, abdominal binders, sacro lumbar magnet supports, and magnetic therapy wraps.
- Vertos Medical, Inc.
- Medical device company focused on the treatment of debilitating spinal conditions. Pioneered percutaneous interventional devices used in the treatment of lumbar spinal stenosis (LSS) and with the mild (Minimally Invasive Lumbar Decompression) procedure.
- Zimmer (2)
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