- DaDa Detective
 - Weekly online comic strip featuring the DaDa Detective. New comics are posted every Monday. - Daily Cartoon, A
- Visit the off-the-wall humour of Paul Dlugokencky. Enjoy a new colour cartoon daily.
- Daily Feed, The
- Daily comic strip features created six days a week for feed distribution.
- Day by Day
- Lampooning office politics at a high-tech company.
- Day to Day
- Single panel cartoon by Deborah Peyton.
- Daze of Our Lives
- State-of-the-art 19th century humour.
- Death Gets a Web Site
- This is Death. He's just this guy.
- Death of the Party
- Political comic strip for people who hate politics.
- Demonology 101
- Online comic by Faith Erin Hicks about high school and other forces of evil.
- Desperate Times
- Two guys, a sister, and her boyfriend who dresses in an amusement park costume.
- Detective Fork
- Noir comic strip starring silverware.
- Devils Coachmen, The
- Online comic about the coachmen to the devil.
- Dharma The Cat
- Philosophical cartoon site that also has an Inter-Faith Forum, Humour and an introduction to Buddhism.
- Dick Tracy (1)
- Diesel Sweeties
- There may be funnier comics out there, but there are none as lowbrow or low-rez.
- Dilbert (6)
- Find out about Dilbert, the American comic strip written and drawn by Scott Adams where the title character, Dilbert is an engineer with satirical humour working in a white collar, micromanaged office. Sites feature daily strips, archives, games, merchandise, photo galleries, virtual tour, pretending-to-work games, and profile of Scott Adams.
- Dinette Set, The (2)
- dizABLED w/Leeder O. Men
- Witness the heartwarming episodes of the world famous wheelchair stuntman!
- Doctor Fun (2)
- Doctor Pepper Show, The
- Comic set in a world where evil doctors rule, girls wear frilly underpants, and people use their manners.
- Dodge and Burn
- Web comic starring Dodge the Anteater and Burn the Capybara, the worst bug exterminators in South America. Includes fun facts about South American animals, bugs, and the countries of South America.
- Dogma
- Weekly comic strip by Will Mainor, set in idyllic Dogma County.
- Dogz
- Comic panel with peculiar and sometimes perverse themes.
- Doodie.com
- Offers several interactive cartoons featuring characters...uh...pooping.
- Doonesbury (4)
- Dot and Com
- Created by Jerry Leibowitz. Dot and Com, respectively Dorothy Wiliger and Comice Penley, share life's experiences by email.
- Down to Earth
- A look at daily life in Hell. By Gavin Chafin and Steve Wood.
- Dr. Lobster & Steve
- Violence, intrigue, mayhem, and sometimes even a plot.
- Drabble
- Dragon Tails
- The crazy and comic adventures of eight baby dragons.
- Dreamland
- Chronicles a young woman's spiraling journey into the macabre world that lies just beneath the surface of reality.
- Dross Comics
- Dope comics by Drew Ross look to create a fountain-head of underground comics on the Web.
- Dungeon Crawl, Inc.
- Satirizes the Dungeons & Dragons culture by featuring lots of violence and scantily clad women.
- Duplex, The
- Dustinland
- A comic so funny, it'll make you stop drinking water.
- Dykes To Watch Out For@
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