- Maakies
 - Official site for the comic by Tony Millionaire featuring weekly strip, archives, and interviews. - Mac Hall
- Created by Matt Boyd and Ian McConville.
- Mad at the World Comics
- Comic strip about the mad mad world we live in, from the perspective of an Asian Pacific American.
- Madam and Eve
- Daily comic strip from South Africa.
- Mafalda (1)
- Making It: A Survival Guide For Today
- Started in 1985, Keith Robinson's comic strip appears in newspapers across the U.S. Current and archive cartoons on the web site are changed weekly.
- Mallard Fillmore
- Mama's Boyz
- About an African American family living in a large city.
- Mandrake The Magician
- Mark 700
- He's not a violent guy - he simply defends himself against unfair and cowardly attacks.
- Mark Trail (1)
- Marmaduke (1)
- Married To The Sea
- "The champagne of comics" delivers social commentary about modern life and the slow erosion of human dignity thanks to technology.
- Marvin
- Mary Worth (2)
- Masters of the Art
- Webcomic by Justin Pixler and Patrick Johnson.
- MegaTokyo
- Online Manga comic.
- Melonpool
- Daily-updated comic strip that follows the adventures of three aliens, a telepathic dog, and a five-foot tall, 220 lb hamster.
- Men In Hats
- Gripping daily comic by Aaron Farber about six guys who stand around in the desert talking. Sometimes they have breakfast.
- Middletons, The
- Features daily comics, a fan forum, and character biographies.
- Mike Panda
- Minnie Pauz
- Provides cartoons about menopause.
- Mister Boffo
- 3 daily features including: Mister Boffo, Willy 'n' Ethel, and Porterfield from nationally syndicated comic strip artist, Joe Martin.
- Modest Destiny, A
- Ongoing comic by Sean Howard in a Japanese RPG style.
- Modesty Blaise
- Probably the first truely independent realistic heroine in the history of comics
- Mojave
- Writen by Derick Soto.
- Monkey, The
- Based on a true story of a Chinese monk, Xuan Zang, who travelled on foot to what is today India to seek for the Sutra, the Buddhist holy book.
- Mooney the Turtle
- Semi-weekly comic detailing the adventures of a caricature artist turtle named Mooney.
- Moose Miller
- Mostly Business
- Mostralfonso
- Daily comic strip about a small abominable snowman.
- Mother Goose and Grimm (2)
- Movie Punks
- Web comic by Carrington Vanston about going to the movies.
- Mr. Chuck Show featuring Ned and Stumpy
- Weekly comic strip about a talking dog who has his own TV show. The strip becomes funnier if you're drunk.
- Mr. Doobie
- The little black and white cartoon that talks about the gray areas of life in a colourful way.
- Mr. Nice
- Satirical cartoon character fighting the forces of rudeness.
- Muddy Feet
- Features the continuing adventures of Monty and Bob, two DEA agents stuck together as they travel the world fighting the war on drugs.
- Mungo and Mouse
- A radically different comic strip novel.
- Mutts (3)
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