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- Personal Improvement Computer Systems, Inc.
 - Reston - Offers DietMate, a palm-sized self-help computer for weight, cholesterol, and blood pressure control.
- Health Care Management
- Active Health Management
- Chantilly - Applying evidence-based medicine and optimal treatment approaches using clinical matrices to improve clinical outcomes, reduce medical errors, and identify high risk patients.
- Actualize.net
- Silver Spring - Provides online billing and practice management software to mental health providers and clinics. Includes electronic submission of insurance claims.
- Apache Medical Systems
- Provides products and services designed to reduce costs and improve quality at the point of care with objective severity-adjusted individual patient health status measures.
- Compucare Company, The
- Reston - Provides information systems to hospitals and associated heathcare companies.
- Health Cost Consultants, Inc.
- Reston - MedAdvice 2001 software and services provide utilization and case management, workers comp, and clinical guideline solutions nationwide.
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