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• Exploding Dog - Send Sam a title, then he will draw what he feels.
• Errant Story - By Michael Poe.
• Exploitation Now - Daily comic strip with an adult theme by Michael Poe.
• El Goonish Shive - Daily strip by Dan Shive.
• Elf Life - Daily strip by Carson Fire.
• Elf Only Inn - By Josh Sortelli.
• Elftor - The adventures of an angry right-wing pixie who lives in a comic strip.
• Exercises in Style - Comic strip by Matt Madden inspired by the work of French writer Raymond Queneau.
• Elephantitis of the Mind - A new funny and poignant cartoon every day.
• Escape! - Useful and entertaining comic strip by Andrea Beniamino Previtera.
• Enviro-Babies - Champions environmental awareness of endangered, threatened, and rare species. Hoping to build awareness about the precarious state of our planet.
• Externality - Comic strip by Daniel Merlin Goodbrey created in a unique way using Macromedia Flash.