- SETI@home@
- Folding@home
 - Distributed client aimed at using idle CPU power via a screen saver to help simulate protein folding. - World Community Grid
- Project to create the largest public computing grid benefiting humanity.
- Globus Project, The
- Developing basic software infrastructure for computations that integrate geographically distributed computational and information resources.
- ClimatePrediction.net
- Encourages PC users to download a screensaver-style climate modelling programme that will help generate the world's largest climate forecasting experiment.
- Grub
- Open source, distributed Internet crawler.
- Genome@home
- Distributed computing project to understand the genome by reverse engineering new protein sequences for existing folds. Led by the Pande Group at Stanford University.
- Fight AIDS @ Home
- Distributed computing project which uses idle computer time on your personal computer to accelerate anti-HIV drug design research. Download a programme onto your Internet-connected home workstation to participate.
- Compute Against Cancer
- Philanthropic distributed computing effort spanning research in cancer prevention, treatment, cure, and support.
- Particle Physics Data Grid
- Collaboration formed to enable the worldwide distributed computing model of current and future high-energy and nuclear physics experiments.
- Find-a-Drug
- Runs a series of projects in parallel addressing a number of diseases and utilizes THINK software to help evaluate the interactions of billions of molecules with proteins.
- Distributed.net - Project RC5
- Mailing list archives and discussion groups.
- Caltech Infospheres Group
- Deals with the theory and implementation of compositional systems that support peer-to-peer communication among persistent multithreaded distributed objects.
- Millipede Project
- Developing technologies for high performance, virtual parallel machines in distributed environments.
- Avalanche Scalable Multiprocessor Design Project
- Aimed at the significant reduction of effective memory latency in support of both cache-coherent Distributed Shared Memory and Message Passing applications.
- In-silico Screening for Anthrax Toxin Inhibitors@
- DOE Science Grid
- Objective is to provide the advanced distributed computing infrastructure based on Grid middleware and tools to enable the degree of scalability in scientific computing necessary for DOE to accomplish its missions in science.
- sharkGrid
- Part of the ECOCEAN Whaleshark Photo-identification Library, sharkGrid allows you to donate spare cycles of your computer to whale shark research.
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